Coming up, a cure for diabetes
http://www.care-diabetes-india.com/
A potential new cure for diabetes is within sight, based on advances in cell therapy, thanks to the work of Tel Aviv University researchers.
Diabetes is a debilitating condition that afflicts eight percent of Americans and can lead to blindness, kidney failure, strokes and heart disease.
Shimon Efrat of Tel Aviv University's Sackler Faculty of Medicine has developed a way to cultivate cells derived from insulin-producing beta cells from human tissue in the lab. It may be possible to implant these new healthy cells into patients with type 1 diabetes.
If successful, this method, which artificially replicates the insulin cells people need, could ensure that fewer people will die while waiting for a life-saving pancreas and kidney.
Efrat's research paves the way for new and alternative forms of treatment in cases in which organ transplantation is not an option. And one day, the procedure may become as simple as a blood transfusion.
Type 1 diabetes, the most severe form of the condition, emerges in childhood or early adulthood, when the body's immune system stops working properly and destroys the beta cells in the pancreas.
Beta cells are needed to produce insulin, and a shortage of insulin inhibits the breakdown of food into energy. By the time a diagnosis is made, most beta cells are destroyed beyond repair. Injections of insulin can ease the symptoms, but some sufferers from the disease eventually require extreme measures, such as organ transplants, to stay alive.
"The shortage of organ donors makes the development of new cell sources for cell therapy critical," said Efrat. "Using beta cell expansion, we are able to grow a massive reserve of healthy cells that may be made to produce enough insulin to restore the function of the destroyed cells."
Compared to previous research, Efrat's work has increased the number of human beta cells successfully.
"In theory, cells from one donor can be multiplied thousands of times," said Efrat, explaining that the next hurdle will be to "convince" these beta cells to produce insulin in the human body.
Another major hurdle he faces is to get a body's immune system to accept these new cells when transplanted. Human clinical trials, Efrat cautioned, may not begin for another five years or more.
The research was featured in the journal, Diabetes.
Coming up, a cure for diabetes
http://www.care-diabetes-india.com/
Juvenile Diabetes rising in India
| Diabetes |
| Diabetes Cure |
| Diet diabetes |
| Insulin |
| Diabetes Treatment |
| Glucose Monitoring |
| Diabetes Complications |
| Hypoglycemia |
| Foot care |
| Eyes care |
| Kidneys care |
| Diabetes symptom |
| Juvenile diabetes |
| Diabetes management |
| Insulin pumps |
| Insulin pens |
| Insulin injections |
| Diabetes recipe |
| Indian Diabetes recipe |
| Calculate carbohydrate |
| Progress of the childhood diabetes: |
| Diabetes in children progresses through certain definite stages: In the first stage: The disease may appear at the very early age. It deteriorates very rapidly and may be admitted in comatose state. Five years old girl was admitted in coma when it was diagnosed as diabetic ketoacidosis with plasma glucose level over 600mg%. At the discharge, the child is stabilized to the extent, that he is outwardly free from his symptoms of polyurea, polydipsia and lethargy. |
| In the second stage: There is a period when the child's insulin requirement is less than dose prescribed at the time of discharge from the hospital. This is called "honey-moon period" or "remission period". This stage means that his beta cells are still producing some insulin, but is not sufficient enough to keep the child free from diabetes. Only one dose insulin in the morning is sufficient to lower the blood glucose level under control for the whole day. This period lasts for months or years. |
| In the third stage: Beta cells stop secreting insulin. The blood sugar control is totally dependent on exogenous insulin and the insulin requirement rises. Fourth stage is puberty: To control of diabetes at this stage is very difficult for a number of both physiological and emotional reasons. The more problems are faced with girls. Insulin requirement is more in adolescence. |
| Usually if diabetes appear at the age of ten or eleven, there may not be the stage of stage of "honey - moon period". Third and fourth stage comes very quickly. Some children never show a clear " honey-moon period" |
| LONG TERM VIEWS OF THE CHILDHOOD DIABETES |
| School performance:- Intellectual performance of the diabetic child is normal or slightly. Probably, the disease makes him more conscious than others. Usually the good school performance is not observed with the depressed children may be because of lack of family supports . |
| Sports & Occupation |
| The diabetic child can join any kind of sport provided they are properly educated, such as taking a little extra carbohydrate before participating any sport. They should join the armed forces or drive any vehicle including plane where lives of so many people are at risk. Professional careers are suitable for the diabetic children. |
| Marriage |
| There is no bar to marriage. The diabetic should not choose another diabetic as his life partner where chances of diabetic offspring are more than the non-diabetics . |
Juvenile DiabetesType 1
Monday, September 8, 2008
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